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3-hydroxyacyl-coenzyme A dehydrogenase : ウィキペディア英語版
3-hydroxyacyl-CoA dehydrogenase

In enzymology, a 3-hydroxyacyl-CoA dehydrogenase () is an enzyme that catalyzes the chemical reaction
:(S)-3-hydroxyacyl-CoA + NAD+ \rightleftharpoons 3-oxoacyl-CoA + NADH + H+
Thus, the two substrates of this enzyme are (S)-3-hydroxyacyl-CoA and NAD+, whereas its 3 products are 3-oxoacyl-CoA, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.
== Isozymes ==

In humans, the following genes encode proteins with 3-hydroxyacyl-CoA dehydrogenase activity:
* HADH – Hydroxyacyl-Coenzyme A dehydrogenase
* HSD17B10 – 3-Hydroxyacyl-CoA dehydrogenase type-2
* EHHADH – Peroxisomal bifunctional enzyme
* HSD17B4 – Peroxisomal multifunctional enzyme type 2

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